PyOpenWorm.channelworm module¶

class PyOpenWorm.channelworm.ChannelModel(modelType=False, *args, **kwargs)[source]¶

A model for an ion channel.

There may be multiple models for a single channel.

Parameters:

modelType : DatatypeProperty: What this model is based on (either “homology” or “patch-clamp”)

Attributes:

modelType : DatatypeProperty: Passed in on construction
ion : DatatypeProperty: The type of ion this channel selects for
gating : DatatypeProperty: The gating mechanism for this channel (“voltage” or name of ligand(s) )
references : Property: Evidence for this model. May be either Experiment or Evidence object(s).
conductance : DatatypeProperty: The conductance of this ion channel. This is the initial value, and should be entered as a Quantity object.
Example usage::: # Create a ChannelModel >>> cm = P.ChannelModel() # Create Evidence object >>> ev = P.Evidence(author=’White et al.’, date=‘1986’) # Assert >>> ev.asserts(cm) >>> ev.save()

class PyOpenWorm.channelworm.HomologyChannelModel(**kwargs)[source]¶: Bases: PyOpenWorm.channelworm.ChannelModel

class PyOpenWorm.channelworm.PatchClampChannelModel(**kwargs)[source]¶: Bases: PyOpenWorm.channelworm.ChannelModel

class PyOpenWorm.channelworm.PatchClampExperiment(reference=False, **kwargs)[source]¶

Store experimental conditions for a patch clamp experiment.

Attributes:

Ca_concentration : DatatypeProperty: Calcium concentration
Cl_concentration : DatatypeProperty: Chlorine concentration
blockers : DatatypeProperty: Channel blockers used for this experiment
cell : DatatypeProperty: The cell this experiment was performed on
cell_age : DatatypeProperty: Age of the cell
delta_t : DatatypeProperty
duration : DatatypeProperty
end_time : DatatypeProperty
extra_solution : DatatypeProperty
initial_voltage : DatatypeProperty: Starting voltage of the patch clamp
ion_channel : DatatypeProperty: The ion channel being clamped
membrane_capacitance : DatatypeProperty: Initial membrane capacitance
mutants : DatatypeProperty: Type(s) of mutants being used in this experiment
patch_type : DatatypeProperty: Type of patch clamp being used (‘voltage’ or ‘current’)
pipette_solution : DatatypeProperty: Type of solution in the pipette
protocol_end : DatatypeProperty
protocol_start : DatatypeProperty
protocol_step : DatatypeProperty
start_time : DatatypeProperty
temperature : DatatypeProperty
type : DatatypeProperty